INO5042, a thiazole fused 1,4-naphthoquinone compound, and exhibits anti-inflammation activity.

Product information

CAS Number: 14782-19-5

Molecular Weight: 281.29

Formula: C15H7NO3S

Chemical Name: 2-(furan-2-yl)-4H,9H-naphtho[2,3-d][1,3]thiazole-4,9-dione

Smiles: O=C1C2N=C(SC=2C(=O)C2=CC=CC=C12)C1=CC=CO1

InChiKey: VJKZUTFFMNSTTD-UHFFFAOYSA-N

InChi: InChI=1S/C15H7NO3S/c17-12-8-4-1-2-5-9(8)13(18)14-11(12)16-15(20-14)10-6-3-7-19-10/h1-7H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 2 mg/mL (7.11 mM; ultrasonic and adjust pH to 3 with HCl).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

When INO5042 is added to endothelial cells, a shift of velocities is observed towards fast speeds (from 3-5 to 7-11 microm/sec). The same results is significantly found when neutrophils, alone or along with endothelium, has been submitted to INO5042, the number of stickers and rollers being reduced as well.

Products are for research use only. Not for human use.