WDR5 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91450-50, BS91450-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P61964(Human) P61965(Mouse) Q498M4(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC

All Applications: WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100

Background: Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: WDR5 polyclonal antibody detects endogenous levels of WDR5 protein.

Bioworld Molecular Weight: 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of WDR5 on different cell lysates using anti-WDR5 antibody at 1/1,000 dilution.
Positive control:
Lane 1: Hela
Lane 2: A549
Lane 3: NIH-3T3
Lane 4: PC-12, Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-WDR5 antibody. Counter stained with hematoxylin.

Alternative Name: WDR5, BIG3, 2410008O07Rik, AA408785, AA960360, BIG 3, Big, BIG3, BMP2 induced 3 kb gene protein, BMP2 induced gene, 3-KB, BMP2-induced 3-kb gene protein, MGC114572, OTTHUMP00000162494, SWD 3, SWD3, SWD3 Set1c WD40 repeat protein homolog, WD repeat containing protein 5, WD repeat domain 5, WD repeat protein 5, WD repeat-containing protein 5, WD repeat-containing protein BIG-3, WDR 5, Wdr5, WDR5,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified