CRM1 (Acetyl Lys568) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1133-50, ES1133-100

Citations, Manuals and MSDS Available upon request.

Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],

Alternate Name: XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 125kD

Human Gene ID: 7514

Human SWISS Prot NO: O14980

Subcellular Location: Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.

Research Use Only